Share this post on:

product name Benidipine HCl


Description: Benidipine (also known as SC-278724, KW-3049 and Coniel) HCl is the hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker used to treat hypertension and angina pectoris. It also inhibits aldosterone-induced MCR activation. In addition, benidipine Hydrochloride has been reported to reduce oxidative stress. Benidipine is sold in the United States under the proprietary name Sular. Nisoldipine has tropism for cardiac blood vessels.

References: Methods Find Exp Clin Pharmacol. 2005 Apr;27(3):167-71; J Cardiovasc Pharmacol. 1999 Aug;34(2):248-53.



Molecular Weight (MW)

542.02 
Formula

C28H31N3O6.HCl 
CAS No.

91599-74-5 
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 8 mg/mL (14.8 mM)
Water: <1 mg/mL
Ethanol: <1 mg/mL
Solubility (In vivo)

 
Synonyms

KW-3049 

other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19403685

In Vitro

In vitro activity


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References  

Degarelix

Share this post on:

Author: Sodium channel

Share this post on:

product name Benidipine HCl


Description: Benidipine (also known as SC-278724, KW-3049 and Coniel) HCl is the hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker used to treat hypertension and angina pectoris. It also inhibits aldosterone-induced MCR activation. In addition, benidipine Hydrochloride has been reported to reduce oxidative stress. Benidipine is sold in the United States under the proprietary name Sular. Nisoldipine has tropism for cardiac blood vessels.

References: Methods Find Exp Clin Pharmacol. 2005 Apr;27(3):167-71; J Cardiovasc Pharmacol. 1999 Aug;34(2):248-53.



Molecular Weight (MW)

542.02 
Formula

C28H31N3O6.HCl 
CAS No.

91599-74-5 
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 8 mg/mL (14.8 mM)
Water: <1 mg/mL
Ethanol: <1 mg/mL
Solubility (In vivo)

 
Synonyms

KW-3049 

other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19403685

In Vitro

In vitro activity


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References  

Degarelix

Share this post on:

Author: Sodium channel