product name Benidipine HCl
Description: Benidipine (also known as SC-278724, KW-3049 and Coniel) HCl is the hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker used to treat hypertension and angina pectoris. It also inhibits aldosterone-induced MCR activation. In addition, benidipine Hydrochloride has been reported to reduce oxidative stress. Benidipine is sold in the United States under the proprietary name Sular. Nisoldipine has tropism for cardiac blood vessels.
References: Methods Find Exp Clin Pharmacol. 2005 Apr;27(3):167-71; J Cardiovasc Pharmacol. 1999 Aug;34(2):248-53.
542.02
Formula
C28H31N3O6.HCl
CAS No.
91599-74-5
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 8 mg/mL (14.8 mM)
Water: <1 mg/mL
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
KW-3049
other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19403685
In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
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In Vivo | |
Animal model | |
Formulation & Dosage | |
References |
Author: Sodium channel
product name Benidipine HCl
Description: Benidipine (also known as SC-278724, KW-3049 and Coniel) HCl is the hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker used to treat hypertension and angina pectoris. It also inhibits aldosterone-induced MCR activation. In addition, benidipine Hydrochloride has been reported to reduce oxidative stress. Benidipine is sold in the United States under the proprietary name Sular. Nisoldipine has tropism for cardiac blood vessels.
References: Methods Find Exp Clin Pharmacol. 2005 Apr;27(3):167-71; J Cardiovasc Pharmacol. 1999 Aug;34(2):248-53.
542.02
Formula
C28H31N3O6.HCl
CAS No.
91599-74-5
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 8 mg/mL (14.8 mM)
Water: <1 mg/mL
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
KW-3049
other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19403685
In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
---|---|
In Vivo | |
Animal model | |
Formulation & Dosage | |
References |