product name Clevidipine Butyrate
Description: Clevidipine is a dihydropyridine L-type calcium channel blocker, which is highly selective for vascular, as opposed to myocardial, smooth muscle and, therefore, has little or no effect on myocardial contractility or cardiac conduction. It is uses as an antihypertensive agent for the reduction of blood pressure. It reduces mean arterial blood pressure by decreasing systemic vascular resistance. Clevidipine does not reduce cardiac filling pressure, confirming lack of effects on the venous capacitance vessels.
References: J Pediatr Pharmacol Ther. 2015 Jan-Feb;20(1):54-60.
456.32
Formula
C21H23Cl2NO6
CAS No.
167221-71-8
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 91 mg/mL (199.4 mM)
Water: < 1 mg/mL
Ethanol: 3 mg/mL (6.6 mM)
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19403632
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |
Related Posts
product name Clevidipine Butyrate
Description: Clevidipine is a dihydropyridine L-type calcium channel blocker, which is highly selective for vascular, as opposed to myocardial, smooth muscle and, therefore, has little or no effect on myocardial contractility or cardiac conduction. It is uses as an antihypertensive agent for the reduction of blood pressure. It reduces mean arterial blood pressure by decreasing systemic vascular resistance. Clevidipine does not reduce cardiac filling pressure, confirming lack of effects on the venous capacitance vessels.
References: J Pediatr Pharmacol Ther. 2015 Jan-Feb;20(1):54-60.
456.32
Formula
C21H23Cl2NO6
CAS No.
167221-71-8
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 91 mg/mL (199.4 mM)
Water: < 1 mg/mL
Ethanol: 3 mg/mL (6.6 mM)
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19403632
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |