product name Diltiazem HCl
Description: Diltiazem HCl (also known as Tiazac,RG 83606 HCl) is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions. Chemically, Diltiazem is classified as a nondihydropyridines (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia. It relaxes the smooth muscles in the walls of arteries, which opens (dilates) the arteries, allows blood to flow more easily, and lowers blood pressure.
References: Jpn Heart J. 1977 Mar;18(2):235-45.
450.98
Formula
C22H26N2O4S.HCl
CAS No.
33286-22-5
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 90 mg/mL (199.6 mM)
Water: 90 mg/mL (199.6 mM)
Ethanol: 4 mg/mL (8.9 mM)
Solubility (In vivo)
Synonyms
RG 83606 HCl
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19403519
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |
Related Posts
product name Diltiazem HCl
Description: Diltiazem HCl (also known as Tiazac,RG 83606 HCl) is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions. Chemically, Diltiazem is classified as a nondihydropyridines (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia. It relaxes the smooth muscles in the walls of arteries, which opens (dilates) the arteries, allows blood to flow more easily, and lowers blood pressure.
References: Jpn Heart J. 1977 Mar;18(2):235-45.
450.98
Formula
C22H26N2O4S.HCl
CAS No.
33286-22-5
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 90 mg/mL (199.6 mM)
Water: 90 mg/mL (199.6 mM)
Ethanol: 4 mg/mL (8.9 mM)
Solubility (In vivo)
Synonyms
RG 83606 HCl
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19403519
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |