product name Propranolol HCl
Description: Propranolol HCl (also known as AY-64043, ICI-45520, NCS-91523) is a competitive and non-selective beta-adrenergic receptors inhibitor with IC50 of 12 nM. It blocks bothh β1 and β2 adrenergic receptors. Propranolol hydrochloride also has been shown to inhibit the formation of phospholipase D-derived diacylglycerol by inhibiting cytosolic phosphatidate phosphohydrolase; making propranolol a useful tool for investigating phospholipase C-/D-mediated DAG production.
References: Mol Pharmacol. 1996 Jan;49(1):198-206.
295.8
Formula
C16H21NO2.HCl
CAS No.
318-98-9
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 59 mg/mL (199.5 mM)
Water: 6 mg/mL (20.3 mM)
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
AY-64043, ICI-45520, NCS-91523
other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19398885
In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
---|---|
In Vivo | |
Animal model | |
Formulation & Dosage | |
References |
Author: Sodium channel
product name Propranolol HCl
Description: Propranolol HCl (also known as AY-64043, ICI-45520, NCS-91523) is a competitive and non-selective beta-adrenergic receptors inhibitor with IC50 of 12 nM. It blocks bothh β1 and β2 adrenergic receptors. Propranolol hydrochloride also has been shown to inhibit the formation of phospholipase D-derived diacylglycerol by inhibiting cytosolic phosphatidate phosphohydrolase; making propranolol a useful tool for investigating phospholipase C-/D-mediated DAG production.
References: Mol Pharmacol. 1996 Jan;49(1):198-206.
295.8
Formula
C16H21NO2.HCl
CAS No.
318-98-9
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 59 mg/mL (199.5 mM)
Water: 6 mg/mL (20.3 mM)
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
AY-64043, ICI-45520, NCS-91523
other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19398885
In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
---|---|
In Vivo | |
Animal model | |
Formulation & Dosage | |
References |