product name Synephrine
Description: Synephrine, a natural protoalkaloid in the extract of bitter orange and other citrus species, is commonly used for weight loss. Synephrine has gained significant popularity as an alternative to ephedrine. Products containing bitter orange or synephrine are suspected of causing adverse cardiovascular reactions. Synephrine can stimulate glucose consumption (Glut4-dependent glucose uptake) by stimulating AMPK activity, regardless of insulin-stimulated PI3 kinase-Akt activity in L6 skeletal muscle cells.
References: Int J Med Sci. 2012;9(7):527-38; Biochem Biophys Res Commun. 2012 Feb 24;418(4):720-4.
167.21
Formula
C9H13NO2
CAS No.
94-07-5
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 33 mg/mL (197.34mM)
Water: <1 mg/mL
Ethanol: 2 mg/mL (12 mM)
Solubility (In vivo)
Synonyms
Oxedrine
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19398448
| In Vitro |
In vitro activity: Synephrine is a compound commonly used for weight loss. Synephrine has gained significant popularity as an alternative to ephedrine. Products containing bitter orange or synephrine are suspected of causing adverse cardiovascular reactions. Synephrine can stimulate glucose consumption (Glut4-dependent glucose uptake) by stimulating AMPK activity, regardless of insulin-stimulated PI3 kinase-Akt activity in L6 skeletal muscle cells. Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References | Int J Med Sci. 2012;9(7):527-38; Biochem Biophys Res Commun. 2012 Feb 24;418(4):720-4. |
Related Posts
product name Synephrine
Description: Synephrine, a natural protoalkaloid in the extract of bitter orange and other citrus species, is commonly used for weight loss. Synephrine has gained significant popularity as an alternative to ephedrine. Products containing bitter orange or synephrine are suspected of causing adverse cardiovascular reactions. Synephrine can stimulate glucose consumption (Glut4-dependent glucose uptake) by stimulating AMPK activity, regardless of insulin-stimulated PI3 kinase-Akt activity in L6 skeletal muscle cells.
References: Int J Med Sci. 2012;9(7):527-38; Biochem Biophys Res Commun. 2012 Feb 24;418(4):720-4.
167.21
Formula
C9H13NO2
CAS No.
94-07-5
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 33 mg/mL (197.34mM)
Water: <1 mg/mL
Ethanol: 2 mg/mL (12 mM)
Solubility (In vivo)
Synonyms
Oxedrine
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19398448
| In Vitro |
In vitro activity: Synephrine is a compound commonly used for weight loss. Synephrine has gained significant popularity as an alternative to ephedrine. Products containing bitter orange or synephrine are suspected of causing adverse cardiovascular reactions. Synephrine can stimulate glucose consumption (Glut4-dependent glucose uptake) by stimulating AMPK activity, regardless of insulin-stimulated PI3 kinase-Akt activity in L6 skeletal muscle cells. Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References | Int J Med Sci. 2012;9(7):527-38; Biochem Biophys Res Commun. 2012 Feb 24;418(4):720-4. |