product name DL-Adrenaline
Description: DL-Adrenaline [also known as (±)-Epinephrine] is a hormone and a neurotransmitter secreted by the medulla of the adrenal glands. (±)-Epinephrine is an adrenoceptor agonist. The L-form is a direct-acting sympathomimetic agent with pronounced effect on alpha- and beta-adrenergic receptors. Its action is likened to endogenous adrenaline released from the adrenal medulla in response to extreme physiological conditions.
References: Am J Physiol. 1982 Apr;242(4):H593-601; Br J Dis Chest. 1986 Jan;80(1):1-6.
183.2
Formula
C9H13NO3
CAS No.
329-65-7
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: <1 mg/mL
Water: <1 mg/mL
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19398132
In Vitro |
In vitro activity: Epinephrine is a hormone and a neurotransmitter. The investigation of the pharmacology of epinephrine made a major contribution to the understanding of the autonomic system and the function of the sympathetic system. Epinephrine remains a useful medicine for several emergency indications. This is despite its non-specific action on adrenoceptors and the subsequent development of multiple selective medicines that target subtypes of the adrenoceptors. The word adrenaline is used in common parlance to denote increased activation of the sympathetic system associated with the energy and excitement of the fight-or-flight response, even though this is physiologically inaccurate. The influence of adrenaline is mainly limited to a metabolic effect and bronchodilation effect on organs devoid of direct sympathetic innervation. Kinase Assay: Cell Assay: |
---|---|
In Vivo | |
Animal model | |
Formulation & Dosage | |
References | Am J Physiol. 1982 Apr;242(4):H593-601; Br J Dis Chest. 1986 Jan;80(1):1-6. |
Author: Sodium channel
product name DL-Adrenaline
Description: DL-Adrenaline [also known as (±)-Epinephrine] is a hormone and a neurotransmitter secreted by the medulla of the adrenal glands. (±)-Epinephrine is an adrenoceptor agonist. The L-form is a direct-acting sympathomimetic agent with pronounced effect on alpha- and beta-adrenergic receptors. Its action is likened to endogenous adrenaline released from the adrenal medulla in response to extreme physiological conditions.
References: Am J Physiol. 1982 Apr;242(4):H593-601; Br J Dis Chest. 1986 Jan;80(1):1-6.
183.2
Formula
C9H13NO3
CAS No.
329-65-7
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: <1 mg/mL
Water: <1 mg/mL
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19398132
In Vitro |
In vitro activity: Epinephrine is a hormone and a neurotransmitter. The investigation of the pharmacology of epinephrine made a major contribution to the understanding of the autonomic system and the function of the sympathetic system. Epinephrine remains a useful medicine for several emergency indications. This is despite its non-specific action on adrenoceptors and the subsequent development of multiple selective medicines that target subtypes of the adrenoceptors. The word adrenaline is used in common parlance to denote increased activation of the sympathetic system associated with the energy and excitement of the fight-or-flight response, even though this is physiologically inaccurate. The influence of adrenaline is mainly limited to a metabolic effect and bronchodilation effect on organs devoid of direct sympathetic innervation. Kinase Assay: Cell Assay: |
---|---|
In Vivo | |
Animal model | |
Formulation & Dosage | |
References | Am J Physiol. 1982 Apr;242(4):H593-601; Br J Dis Chest. 1986 Jan;80(1):1-6. |