product name Tizanidine HCl
Description: Tizanidine HCl is a potent α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. It is mainly used as a muscle relaxant for the treatment of the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, ALS, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system.
References: Expert Opin Pharmacother. 2008 Aug;9(12):2209-15.
290.17
Formula
C9H8ClN5S.HCl
CAS No.
64461-82-1
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 10 mg/mL (34.5 mM)
Water: 15 mg/mL (51.69 mM)
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19397913
In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
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In Vivo | |
Animal model | |
Formulation & Dosage | |
References |
Author: Sodium channel
product name Tizanidine HCl
Description: Tizanidine HCl is a potent α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. It is mainly used as a muscle relaxant for the treatment of the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, ALS, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system.
References: Expert Opin Pharmacother. 2008 Aug;9(12):2209-15.
290.17
Formula
C9H8ClN5S.HCl
CAS No.
64461-82-1
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 10 mg/mL (34.5 mM)
Water: 15 mg/mL (51.69 mM)
Ethanol: <1 mg/mL
Solubility (In vivo)
Synonyms
other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19397913
In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
---|---|
In Vivo | |
Animal model | |
Formulation & Dosage | |
References |