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product name Tizanidine HCl


Description: Tizanidine HCl is a potent α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. It is mainly used as a muscle relaxant for the treatment of the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, ALS, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system. 

References: Expert Opin Pharmacother. 2008 Aug;9(12):2209-15.



Molecular Weight (MW)

290.17 
Formula

C9H8ClN5S.HCl 
CAS No.

64461-82-1 
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 10 mg/mL (34.5 mM) 
Water: 15 mg/mL (51.69 mM) 
Ethanol: <1 mg/mL
Solubility (In vivo)

 
Synonyms

 

other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19397913

In Vitro

In vitro activity


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References  

GDC-0834

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Author: Sodium channel

Share this post on:

product name Tizanidine HCl


Description: Tizanidine HCl is a potent α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. It is mainly used as a muscle relaxant for the treatment of the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, ALS, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system. 

References: Expert Opin Pharmacother. 2008 Aug;9(12):2209-15.



Molecular Weight (MW)

290.17 
Formula

C9H8ClN5S.HCl 
CAS No.

64461-82-1 
Storage

-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)

DMSO: 10 mg/mL (34.5 mM) 
Water: 15 mg/mL (51.69 mM) 
Ethanol: <1 mg/mL
Solubility (In vivo)

 
Synonyms

 

other peoduct :References PubMed ID::http://www.ncbi.nlm.nih.gov/pubmed/19397913

In Vitro

In vitro activity


Kinase Assay:


Cell Assay

In Vivo  
Animal model  
Formulation & Dosage  
References  

GDC-0834

Share this post on:

Author: Sodium channel