product name Rivastigmine Tartrate
Description: Rivastigmine Tartrate, also known as ENA-713, is a cholinesterase inhibitor with IC50 of 5.5 μM, it is used as a parasympathomimetic or cholinergic agent for the management of mild to moderate Alzheimer disease, Dementia, and Parkinsons Disease. Rivastigmine is a carbamate-derived reversible cholinesterase inhibitor that is selective for the central nervous system . It acts by covalently modifying a serine residue in the active site by carbamoylation, as it stabilizes or reduces the rate of decline in certain cognitive functions.
References: J Clin Neurol. 2011 Sep;7(3):137-42.
400.42
Formula
C14H22N2O2.C4H6O6
CAS No.
129101-54-8
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 42 mg/mL (104.9 mM)
Water: 80 mg/mL (199.8 mM)
Ethanol: 80 mg/mL (199.8 mM)
Solubility (In vivo)
Synonyms
ENA 713
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19391622
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |
Related Posts
product name Rivastigmine Tartrate
Description: Rivastigmine Tartrate, also known as ENA-713, is a cholinesterase inhibitor with IC50 of 5.5 μM, it is used as a parasympathomimetic or cholinergic agent for the management of mild to moderate Alzheimer disease, Dementia, and Parkinsons Disease. Rivastigmine is a carbamate-derived reversible cholinesterase inhibitor that is selective for the central nervous system . It acts by covalently modifying a serine residue in the active site by carbamoylation, as it stabilizes or reduces the rate of decline in certain cognitive functions.
References: J Clin Neurol. 2011 Sep;7(3):137-42.
400.42
Formula
C14H22N2O2.C4H6O6
CAS No.
129101-54-8
Storage
-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)
DMSO: 42 mg/mL (104.9 mM)
Water: 80 mg/mL (199.8 mM)
Ethanol: 80 mg/mL (199.8 mM)
Solubility (In vivo)
Synonyms
ENA 713
other peoduct :References PubMed ID：:http://www.ncbi.nlm.nih.gov/pubmed/19391622
| In Vitro |
In vitro activity: Kinase Assay: Cell Assay: |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References |