Product Name :
Tiopinac
Description:
Tiopinac (RS 40974), a dibenzthiepin, is an orally active and highly potent anti-inflammatory, analgesic and anti-pyretic agent.
CAS:
61220-69-7
Molecular Weight:
284.33
Formula:
C16H12O3S
Chemical Name:
2-{2-oxo-9-thiatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3(8),4,6,11,13-hexaen-6-yl}acetic acid
Smiles :
OC(=O)CC1=CC2SCC3=CC=CC=C3C(=O)C=2C=C1
InChiKey:
KLIVRBFRQSOGQI-UHFFFAOYSA-N
InChi :
InChI=1S/C16H12O3S/c17-15(18)8-10-5-6-13-14(7-10)20-9-11-3-1-2-4-12(11)16(13)19/h1-7H,8-9H2,(H,17,18)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Tiopinac (RS 40974), a dibenzthiepin, is an orally active and highly potent anti-inflammatory, analgesic and anti-pyretic agent.|Product information|CAS Number: 61220-69-7|Molecular Weight: 284.33|Formula: C16H12O3S|Chemical Name: 2-{2-oxo-9-thiatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3(8),4,6,11,13-hexaen-6-yl}acetic acid|Smiles: OC(=O)CC1=CC2SCC3=CC=CC=C3C(=O)C=2C=C1|InChiKey: KLIVRBFRQSOGQI-UHFFFAOYSA-N|InChi: InChI=1S/C16H12O3S/c17-15(18)8-10-5-6-13-14(7-10)20-9-11-3-1-2-4-12(11)16(13)19/h1-7H,8-9H2,(H,17,18)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Baxdrostat} site|{Baxdrostat} Mineralocorticoid Receptor|{Baxdrostat} Technical Information|{Baxdrostat} Data Sheet|{Baxdrostat} supplier|{Baxdrostat} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Chloramphenicol} site|{Chloramphenicol} Anti-infection|{Chloramphenicol} Biological Activity|{Chloramphenicol} In stock|{Chloramphenicol} supplier|{Chloramphenicol} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32544962 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Tiopinac (0.03-110 mg/kg) has 40 times the antiphlogistic potency of phenylbutazone. The dose required to reduce paw swelling by 30% is approximately 0.5 mg/kg. Tiopinac does not elicit overt side effects at the 20 mg/kg/day dose. Tiopinac causes a dose-related reversal of the decreases body weight caused by the adjuvant disease, the weight of those rats receiving 0.135 and 0.4 mg/kg/day being significantly greater than that of the positive controls. Tiopinac (0.3-30 mg/kg) is highly potent in inhibiting the pain evoked in the yeastinflamed hind paw of the rat.|Products are for research use only. Not for human use.|
